Cryo-EM Resource Center for Biomolecular Machines at Southeast Universities
Official title: The Southeastern Center for Microscopy of Macromolecular Machines (SECM4)
Funded at Florida State University · NIH-11379509 · Data updated 2026-11-12
A regional center at Florida State University will provide cryo-electron microscopy services and training to researchers across the Southeast to help determine high-resolution structures of biomolecules.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Florida State University NIH-funded |
| Lab location | 1 site (Tallahassee, United States) |
| Project start | August 1, 2022 |
| Project end | May 31, 2027 |
| Funding year | 2026 |
| Award (this year) | $1,050,295 |
| NIH project number | 5R24GM145964-05 |
| Project ID | NIH-11379509 on NIH RePORTER |
Who could benefit from this research
✓Could help
Researchers and clinicians in the Southeast who study diseases and biomolecular machines and need high-resolution structural data.
✕Less likely to help
Patients will not be directly enrolled or treated; benefits are indirect through accelerated research.
What this research studies
This NIH-funded center will support researchers by offering sample preparation, cryo-EM data collection, data analysis, and training to improve access to high-resolution structural biology. It aims to lower entry barriers and provide affordable services for institutions in the Southeast, including states that have been underserved. By expanding the scope to specimen optimization, screening, processing, and routine analyses, the center helps researchers generate reliable structural data without needing a multi-million dollar microscope. The program emphasizes collaboration, cost-effective usage, and broad access to state-of-the-art cryo-EM capabilities.
Why it matters
Potential benefit: Patients could ultimately benefit from faster, more accurate understanding of disease-related biomolecular structures that inform drug design and diagnostics.
How similar studies have gone: Previous SECM4 generations demonstrated high-resolution data collection, and the new generation expands access and services.
Where this research is happening
-
Florida State University
Tallahassee, United States Active
Researchers
- Principal investigator: Stagg, Scott M — Florida State University
- Study coordinator: Stagg, Scott M
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.