Creating virtual models to predict heart disease treatment outcomes

Digital Twins from the Atom to the Rhythm

NIH-funded research University of California at Davis · NIH-11124221

This study is working on a new technology that creates virtual models of your heart health to better understand how your body responds to different treatments, helping doctors find the most effective and personalized care for heart conditions.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionUniversity of California at Davis NIH-funded
Lab location1 site (Davis, United States)
Project IDNIH-11124221 on NIH RePORTER

What this research studies

This research aims to develop digital twin technology that creates virtual models of patients' physiological processes, specifically focusing on cardiac health. By integrating clinical data, experimental results, and advanced simulations, the project seeks to replicate individual characteristics of heart diseases and predict how patients will respond to various treatments. The approach utilizes deep learning and patient-specific stem cell-derived heart cells to enhance the accuracy of predictions regarding drug efficacy and potential side effects. This innovative method could lead to more personalized and effective treatment strategies for heart conditions.

Who could benefit from this research

Good fit: Ideal candidates for this research are adults over 21 years old who are experiencing cardiac conditions or are at risk for cardiac arrhythmias.

Not a fit: Patients with non-cardiac related health issues or those under 21 years old may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to more tailored and effective treatments for patients with cardiac diseases, improving their health outcomes.

How similar studies have performed: Other research has shown promise in using digital twin technology for various medical applications, indicating a potential for success in this novel approach for cardiac health.

Where this research is happening

Davis, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.