Creating virtual models to predict heart disease treatment outcomes
Official title: Digital Twins from the Atom to the Rhythm
Funded at University of California at Davis · NIH-11124221 · Data updated 2026-11-12
This study is working on a new technology that creates virtual models of your heart health to better understand how your body responds to different treatments, helping doctors find the most effective and personalized care for heart conditions.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of California at Davis NIH-funded |
| Lab location | 1 site (Davis, United States) |
| Project start | July 1, 2024 |
| Project end | May 31, 2028 |
| Funding year | 2025 |
| Award (this year) | $791,630 |
| NIH project number | 5R01HL174001-02 |
| Project ID | NIH-11124221 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are adults over 21 years old who are experiencing cardiac conditions or are at risk for cardiac arrhythmias.
✕Less likely to help
Patients with non-cardiac related health issues or those under 21 years old may not benefit from this research.
What this research studies
This research aims to develop digital twin technology that creates virtual models of patients' physiological processes, specifically focusing on cardiac health. By integrating clinical data, experimental results, and advanced simulations, the project seeks to replicate individual characteristics of heart diseases and predict how patients will respond to various treatments. The approach utilizes deep learning and patient-specific stem cell-derived heart cells to enhance the accuracy of predictions regarding drug efficacy and potential side effects. This innovative method could lead to more personalized and effective treatment strategies for heart conditions.
Why it matters
Potential benefit: If successful, this research could lead to more tailored and effective treatments for patients with cardiac diseases, improving their health outcomes.
How similar studies have gone: Other research has shown promise in using digital twin technology for various medical applications, indicating a potential for success in this novel approach for cardiac health.
Where this research is happening
-
University of California at Davis
Davis, United States Active
Researchers
- Principal investigator: Clancy, Colleen E — University of California at Davis
- Study coordinator: Clancy, Colleen E
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.