Creating vaccines to protect against various coronaviruses
Official title: Development of pan-betacoronavirus vaccines
Funded at University of Pennsylvania · NIH-11042228 · Data updated 2026-11-12
This study is working on creating vaccines that help your body build strong defenses against various coronaviruses, including those that have caused recent outbreaks, so we can be better prepared for any future infections.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Pennsylvania NIH-funded |
| Lab location | 1 site (Philadelphia, United States) |
| Project start | March 3, 2023 |
| Project end | February 29, 2028 |
| Funding year | 2025 |
| Award (this year) | $709,989 |
| NIH project number | 5R01AI170928-03 |
| Project ID | NIH-11042228 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research include individuals who are at risk of exposure to coronaviruses or those who have had previous infections.
✕Less likely to help
Patients who are not at risk for coronavirus infections or those who have already been vaccinated against all known variants may not benefit from this research.
What this research studies
This research focuses on developing vaccines that can generate strong immune responses against different types of coronaviruses, including those that have caused recent pandemics. The approach involves identifying specific sites on the virus that can trigger the production of neutralizing antibodies, which are crucial for preventing infections. By using a rational vaccine design strategy, the researchers aim to create immunogens that can effectively stimulate the immune system to produce long-lasting protection against a range of coronaviruses. This work is essential for preparing for potential future outbreaks.
Why it matters
Potential benefit: If successful, this research could lead to vaccines that provide broad protection against multiple coronaviruses, potentially preventing future pandemics.
How similar studies have gone: Other research has shown promise in developing vaccines targeting coronaviruses, indicating that this approach has potential for success.
Where this research is happening
-
University of Pennsylvania
Philadelphia, United States Active
Researchers
- Principal investigator: Andrabi, Raiees Ahmad — University of Pennsylvania
- Study coordinator: Andrabi, Raiees Ahmad
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.