Creating vaccines to protect against various coronaviruses
The Development and Evaluation of Pan-Coronavirus Vaccines
This study is working on new vaccines to help protect people from current and future coronaviruses, including those that might come from animals, and it's designed for anyone interested in better ways to boost their immune response against these viruses.
Quick facts
| Grant type | P01 program project |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Washington University NIH-funded |
| Lab location | 1 site (Saint Louis, United States) |
| Project ID | NIH-10420511 on NIH RePORTER |
What this research studies
This research focuses on developing new vaccines that can provide broad protection against existing and future coronaviruses, including those that may emerge from animals. The project combines the expertise of multiple laboratories to design and optimize specific antigens that stimulate the immune system's B and T cells. By using advanced techniques, the researchers aim to create vaccines that can be delivered through different methods, including mucosal and systemic routes, to enhance immunity against these viruses. The research involves testing these vaccines in animal models to evaluate their effectiveness in preventing infection and disease.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals who are at risk of exposure to coronaviruses or those who may benefit from enhanced immunity against these viruses.
Not a fit: Patients who are not at risk for coronavirus infections or those who have already been vaccinated against specific coronaviruses may not receive direct benefits from this research.
Why it matters
Potential benefit: If successful, this research could lead to vaccines that protect against a wide range of coronaviruses, potentially preventing future outbreaks.
How similar studies have performed: Other research has shown promise in developing vaccines for coronaviruses, indicating that this approach has potential for success.
Where this research is happening
Saint Louis, United States
- Washington University — Saint Louis, United States (Active)
Researchers
- Principal investigator: Diamond, Michael S — Washington University
- Study coordinator: Diamond, Michael S
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.