Creating vaccines and treatments for cancers linked to HPV.

Development and Characterization of Immunotherapies for HPV-Associated Malignancies

['FUNDING_OTHER'] · JOHNS HOPKINS UNIVERSITY · NIH-10914056

This study is exploring new vaccines and treatments to help prevent and fight cancers linked to HPV, like cervical and throat cancers, and it's designed for patients who may benefit from better options to improve their health and quality of life.

Quick facts

Phase['FUNDING_OTHER']
Study typeNih_funding
SexAll
SponsorJOHNS HOPKINS UNIVERSITY (nih funded)
Locations1 site (BALTIMORE, UNITED STATES)
Trial IDNIH-10914056 on ClinicalTrials.gov

What this research studies

This research focuses on developing innovative vaccines and immunotherapies to prevent and treat cancers associated with human papillomavirus (HPV), particularly cervical and oropharyngeal cancers. The team at Johns Hopkins University is utilizing advanced techniques, including DNA vaccines and gene gun delivery methods, to enhance the effectiveness of these treatments. Patients may benefit from new therapeutic options that are specifically designed to target HPV-related malignancies, with the goal of improving outcomes and quality of life. The research also aims to establish preclinical models and human immunological assays to facilitate future clinical trials.

Who could benefit from this research

Good fit: Ideal candidates for this research are individuals diagnosed with HPV-related malignancies, particularly cervical or oropharyngeal cancers.

Not a fit: Patients with cancers not associated with HPV or those who do not have HPV infections may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to more effective vaccines and treatments for patients suffering from HPV-associated cancers.

How similar studies have performed: Previous research has shown promise in developing immunotherapies for HPV-associated cancers, indicating a potential for success with this approach.

Where this research is happening

BALTIMORE, UNITED STATES

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.

View on NIH RePORTER →

Conditions: Cancer Biology, Cancer Patient, Cervical Cancer, Cervix Cancer, Disease

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.