Creating tools to study HPV16 in throat tissues
Official title: Developing tools to study HPV16 in oropharyngeal tissues
Funded at University of Arizona · NIH-11034194 · Data updated 2026-11-12
This study is looking at how the HPV16 virus might lead to throat cancers, and it's for anyone interested in understanding this connection better, as researchers will create special cell lines from tonsil tissues to learn more about the virus and how different versions of it could influence cancer risk.
Quick facts
| Grant type | R03 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Arizona NIH-funded |
| Lab location | 1 site (Tucson, United States) |
| Project start | November 15, 2024 |
| Project end | October 31, 2026 |
| Funding year | 2025 |
| Award (this year) | $75,013 |
| NIH project number | 1R03AI187892-01 |
| Project ID | NIH-11034194 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are individuals with a history of HPV infection or those diagnosed with oropharyngeal cancer.
✕Less likely to help
Patients who do not have HPV-related conditions or oropharyngeal cancers may not benefit from this research.
What this research studies
This research focuses on understanding how the HPV16 virus contributes to oropharyngeal cancers, which are increasingly common in the U.S. The team will develop specialized cell lines from tonsil tissues to study the virus's lifecycle and its impact on cancer development. By creating these tools, researchers aim to overcome existing technical challenges that hinder progress in this field. The study will also explore how different variants of HPV16 may affect cancer risk and progression.
Why it matters
Potential benefit: If successful, this research could lead to better understanding and potentially new treatments for HPV-related oropharyngeal cancers.
How similar studies have gone: Previous research has shown promise in studying HPV-related cancers, but this specific approach using primary tonsil-derived cells is relatively novel.
Where this research is happening
-
University of Arizona
Tucson, United States Active
Researchers
- Principal investigator: Van Doorslaer, Koenraad — University of Arizona
- Study coordinator: Van Doorslaer, Koenraad
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.