Creating tools to identify specific neurons in the brain
Neuron-SELEX: Development of neuron-specific nanoscale toolkits for single-cell recognition
This study is working on creating tiny tools that can easily mark specific brain cells so scientists can better understand how they work together, helping to unlock the mysteries of the brain without complicated changes to the cells.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Florida NIH-funded |
| Lab location | 1 site (Gainesville, United States) |
| Project ID | NIH-10872163 on NIH RePORTER |
What this research studies
This research focuses on developing advanced nanoscale probes that can quickly label specific neurons in the brain without the need for complex genetic modifications. By using a technique called Neuro-SELEX, the team will create libraries of nucleic acid-based probes that can identify unique neuronal characteristics. This approach aims to enhance our understanding of neural circuits by allowing researchers to visualize and study individual neurons in their natural environment. The goal is to provide innovative tools that can help decipher the complex organization of the brain at a cellular level.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals with neurological conditions or disorders that affect specific neuronal populations.
Not a fit: Patients with conditions unrelated to neuronal identification or those who do not have access to the research facilities may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to breakthroughs in understanding brain function and disorders by enabling precise identification of neurons.
How similar studies have performed: Previous research has shown promise in using similar nanoscale tools for cellular identification, indicating a potential for success in this novel approach.
Where this research is happening
Gainesville, United States
- University of Florida — Gainesville, United States (Active)
Researchers
- Principal investigator: Moroz, Leonid L — University of Florida
- Study coordinator: Moroz, Leonid L
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.