Creating tools to help eliminate human hookworms worldwide
Development of essential research tools for sustaining global programs for the elimination of human hookworms
This study is working on new ways to fight hookworm infections, which can be a big health problem, by creating a special dog model to learn more about the hookworm's biology and genetics, so that we can improve treatments and help people get better care.
Quick facts
| Grant type | R21 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Univ of Massachusetts Med Sch Worcester NIH-funded |
| Lab location | 1 site (Worcester, United States) |
| Project ID | NIH-10544786 on NIH RePORTER |
What this research studies
This research focuses on developing essential tools to combat human hookworm infections, which are a significant public health issue. The project aims to create a novel canine model to study hookworm biology and genetics, as well as to produce a complete genome assembly for the hookworm species A. caninum. By understanding the genetic factors related to drug resistance, the research seeks to enhance global health strategies and improve mass drug administration programs. Patients may benefit from improved diagnostics and treatment options as a result of this work.
Who could benefit from this research
Good fit: Ideal candidates for participation or benefit from this research include individuals affected by hookworm infections, particularly in regions where these parasites are prevalent.
Not a fit: Patients who do not have hookworm infections or are not at risk for these infections may not receive any benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to more effective strategies for eliminating hookworm infections and improving public health outcomes.
How similar studies have performed: Other research has shown success in developing genetic tools for understanding parasitic infections, indicating that this approach has potential for meaningful advancements.
Where this research is happening
Worcester, United States
- Univ of Massachusetts Med Sch Worcester — Worcester, United States (Active)
Researchers
- Principal investigator: Daniels, Rachel Fath — Univ of Massachusetts Med Sch Worcester
- Study coordinator: Daniels, Rachel Fath
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.