Creating tools to detect specific T and B cells in the immune system
Tetramer Core Facility - Development and production of tetramer for CD4 and CD8 T cells
['FUNDING_OTHER'] · EMORY UNIVERSITY · NIH-10489923
This study is working on creating special tools called tetramers that help scientists and doctors find and understand important immune cells, like T cells and B cells, which are key to fighting infections and diseases.
Quick facts
| Phase | ['FUNDING_OTHER'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | EMORY UNIVERSITY (nih funded) |
| Locations | 1 site (ATLANTA, UNITED STATES) |
| Trial ID | NIH-10489923 on ClinicalTrials.gov |
What this research studies
This research focuses on developing and producing specialized reagents known as tetramers that help identify and characterize specific populations of T cells and B cells in the immune system. By utilizing MHC class I and class II tetramers, the project aims to enhance the detection of CD4 and CD8 T cells, which play crucial roles in immune responses. Additionally, the facility is working on creating tetramers for Spike proteins to better understand B cell responses. These reagents will be distributed to researchers and clinicians to improve the evaluation of immune responses in various conditions.
Who could benefit from this research
Good fit: Patients with conditions that affect T and B cell function, such as autoimmune diseases or infections, would be ideal candidates to benefit from this research.
Not a fit: Patients with conditions unrelated to T or B cell responses may not receive any benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to better diagnostic tools and treatments for diseases related to immune system dysfunction.
How similar studies have performed: Previous research has shown success in using tetramer technology for immune cell detection, indicating a promising approach in this area.
Where this research is happening
ATLANTA, UNITED STATES
- EMORY UNIVERSITY — ATLANTA, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: ALTMAN, JOHN — EMORY UNIVERSITY
- Study coordinator: ALTMAN, JOHN
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.