Creating tools to detect immune responses to SARS-CoV-2

NIH TCF Dev and Prod of SARS-CoV-2 Spike tetramers for B Cell Detection

NIH-funded research Emory University · NIH-10282181

This study is working on creating special proteins that help scientists and doctors better understand how our immune system fights COVID-19, so they can improve tests and treatments for people affected by the virus.

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionEmory University NIH-funded
Lab location1 site (Atlanta, United States)
Project IDNIH-10282181 on NIH RePORTER

What this research studies

This research focuses on developing and producing specialized proteins called tetramers that can help identify and analyze specific immune cells, particularly B cells and T cells, that respond to the SARS-CoV-2 virus. By creating these tetramers, the research aims to enhance our understanding of how the immune system reacts to COVID-19 and potential vaccines. The tetramers will be distributed to researchers and healthcare providers to facilitate studies on immune responses in patients affected by COVID-19. This work is crucial for improving diagnostic and therapeutic strategies against the virus.

Who could benefit from this research

Good fit: Ideal candidates for this research are individuals who have been infected with SARS-CoV-2 or are participating in COVID-19 vaccine trials.

Not a fit: Patients who have not been exposed to SARS-CoV-2 or are not involved in related research may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to better tools for diagnosing and understanding immune responses in COVID-19 patients, potentially improving treatment outcomes.

How similar studies have performed: Other research has successfully utilized similar tetramer technology to study immune responses, indicating a promising approach for this investigation.

Where this research is happening

Atlanta, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-09 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.