Creating tools to better understand how biomolecules function
Official title: Developing computational tools to complement experiments in understanding biomolecular function from conformational ensembles
Funded at Georgia State University · NIH-11075346 · Data updated 2026-11-12
This study is working on new computer tools to help scientists better understand how tiny molecules in our bodies work, which could lead to better treatments for patients.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Georgia State University NIH-funded |
| Lab location | 1 site (Atlanta, United States) |
| Project start | May 1, 2024 |
| Project end | April 30, 2029 |
| Funding year | 2025 |
| Award (this year) | $390,000 |
| NIH project number | 5R35GM153718-02 |
| Project ID | NIH-11075346 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for benefiting from this research include individuals with conditions that could be treated through targeted drug therapies informed by biomolecular insights.
✕Less likely to help
Patients with conditions that do not involve biomolecular dysfunction or those not requiring drug therapies may not benefit from this research.
What this research studies
This research focuses on developing advanced computational tools that enhance our understanding of how biomolecules operate by analyzing their dynamic behaviors. By utilizing molecular dynamics simulations, the project aims to uncover detailed mechanisms of biomolecular function that are often challenging to observe through traditional experimental methods. The tools being developed will be rigorously tested and made accessible to the broader scientific community, facilitating drug discovery and biomolecular design. Patients may benefit from the insights gained through this research as it could lead to improved therapeutic strategies.
Why it matters
Potential benefit: If successful, this research could lead to more effective drugs and therapies by providing deeper insights into biomolecular functions.
How similar studies have gone: Other research has shown success in using computational tools to enhance our understanding of biomolecular functions, indicating that this approach is promising.
Where this research is happening
-
Georgia State University
Atlanta, United States Active
Researchers
- Principal investigator: Hamelberg, Donald — Georgia State University
- Study coordinator: Hamelberg, Donald
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.