Creating tools to analyze large brain images
Official title: A Computational Framework for Distributed Registration of Massive Neuroscience Images
Funded at Kitware, INC. · NIH-10259930 · Data updated 2026-11-12
This study is working on new computer tools to help scientists better analyze and compare large brain images from advanced imaging techniques, making it easier to understand how the brain develops and works over time.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Kitware, INC. NIH-funded |
| Lab location | 1 site (Clifton Park, United States) |
| Project start | July 15, 2021 |
| Project end | June 30, 2025 |
| Funding year | 2021 |
| Award (this year) | $1,365,152 |
| NIH project number | 1RF1MH126732-01 |
| Project ID | NIH-10259930 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for participation or benefit from this research would include individuals with neurological conditions or those involved in neuroscience research.
✕Less likely to help
Patients with conditions unrelated to neuroscience or those not engaged in research may not receive direct benefits from this research.
What this research studies
This research focuses on developing advanced computational tools to analyze and register large neuroscience images, particularly those obtained from modern imaging techniques like light-sheet fluorescence microscopy. By creating user-friendly, distributed-computation image registration tools, the project aims to map these images into a common reference frame, allowing researchers to uncover quantitative relationships across different samples and time points. The methodology involves enhancing existing open-source libraries with deep learning techniques to improve the accuracy and efficiency of image analysis. This work could significantly advance our understanding of brain development and function.
Why it matters
Potential benefit: If successful, this research could lead to breakthroughs in understanding brain mechanisms, potentially improving treatments for neurological conditions.
How similar studies have gone: Other research has shown success in using computational methods for image analysis in neuroscience, indicating that this approach has potential for significant advancements.
Where this research is happening
-
Kitware, INC.
Clifton Park, United States Active
Researchers
- Principal investigator: Enquobahrie, Andinet Asmamaw — Kitware, INC.
- Study coordinator: Enquobahrie, Andinet Asmamaw
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.