Creating tissues using advanced 3D bioprinting technology
Official title: High-throughput Spheroid Bioprinting Technology for Scalable Fabrication of Tissues
Funded at Pennsylvania State University, the · NIH-11126620 · Data updated 2026-11-12
This study is exploring a new way to use 3D printing to create tiny clusters of cells that can be shaped into realistic tissue structures, which could help in making better replacements for damaged organs.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Pennsylvania State University, the NIH-funded |
| Lab location | 1 site (University Park, United States) |
| Project start | June 1, 2023 |
| Project end | May 31, 2027 |
| Funding year | 2025 |
| Award (this year) | $488,107 |
| NIH project number | 5R01EB034566-03 |
| Project ID | NIH-11126620 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are individuals with conditions that could benefit from tissue regeneration or replacement, such as those with organ damage or degenerative diseases.
✕Less likely to help
Patients with stable conditions that do not require tissue engineering or those who are not candidates for regenerative therapies may not benefit from this research.
What this research studies
This research focuses on developing a new bioprinting technology that allows for the rapid and precise creation of cellular aggregates, known as spheroids, which can be arranged into complex tissue structures. By overcoming current limitations in spheroid positioning and viability, this approach aims to produce tissues that closely mimic natural organs. The methodology involves high-throughput printing techniques that can work with various sizes of spheroids, enabling the fabrication of scalable tissue constructs for potential medical applications.
Why it matters
Potential benefit: If successful, this research could lead to the development of more effective tissue engineering solutions for regenerative medicine.
How similar studies have gone: Previous research in bioprinting technologies has shown promising results, indicating that this approach could lead to significant advancements in tissue engineering.
Where this research is happening
-
Pennsylvania State University, the
University Park, United States Active
Researchers
- Principal investigator: Ozbolat, Ibrahim — Pennsylvania State University, the
- Study coordinator: Ozbolat, Ibrahim
Related research
Other NIH-funded projects on the same topics.
-
Population Research Institute: Understanding how communities, movement, and social factors shape health across ages
A Pennsylvania State University research center is studying how where people live, move, and participate in families affects health and well‑being from childhood through adulthood.
-
Integrated data platform for infectious disease research using scalable public infrastructure
A large NIH grant funds a platform that makes infectious-disease data easier to access, combine, and analyze using powerful public infrastructure so researchers can work faster and more collaboratively.
-
READI-SET-GO: Improving Delirium Screening for Hospitalized Older Adults
A hospital-based program tests how well routine nurse delirium screening using UB-CAM works when integrated into the electronic health record to improve outcomes for older patients.
-
Healthy Brain and Child Development: a big study following kids from birth through age 10
A large, nationwide study will follow 7,200 mothers and their babies to map how early life experiences shape brain growth and development.
-
How sex differences affect the rewarding feel of aggression in the brain
This grant explores why aggressive experiences feel more rewarding in females and how specific brain circuits and chemical signals shape this in both sexes.
-
How parents' emotions shape young children's anxiety
This project explores how parents' moment-by-moment emotions and bodily signals shape anxiety in children from infancy through age 11.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.