Creating tiny sensors that can detect colorectal cancer through breath analysis
Engineering ingestible nanosensors for breath-based detection of colorectal cancer
['FUNDING_R37'] · GEORGIA INSTITUTE OF TECHNOLOGY · NIH-11049598
This study is testing a new, easy way to spot early signs of colorectal cancer by using tiny sensors that you can swallow, which check your breath for certain enzymes linked to tumors, making it a friendlier option than a colonoscopy.
Quick facts
| Phase | ['FUNDING_R37'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | GEORGIA INSTITUTE OF TECHNOLOGY (nih funded) |
| Locations | 1 site (ATLANTA, UNITED STATES) |
| Trial ID | NIH-11049598 on ClinicalTrials.gov |
What this research studies
This research focuses on developing ingestible nanosensors that can detect early-stage colorectal cancer by analyzing breath. The approach involves engineering these nanosensors to identify specific enzymes in the intestine that are linked to tumor development. By producing detectable signals in breath, this method aims to provide a non-invasive alternative to traditional colonoscopy, which many people avoid due to its invasive nature. The goal is to improve early detection rates and adherence to screening guidelines, ultimately reducing cancer-related deaths.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals at risk for colorectal cancer, particularly those who are hesitant to undergo traditional screening methods like colonoscopy.
Not a fit: Patients who have already been diagnosed with advanced colorectal cancer may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to a simple and non-invasive method for early detection of colorectal cancer, significantly improving patient outcomes.
How similar studies have performed: While the use of ingestible sensors is a novel approach, similar technologies in breath analysis have shown promise in other areas of cancer detection.
Where this research is happening
ATLANTA, UNITED STATES
- GEORGIA INSTITUTE OF TECHNOLOGY — ATLANTA, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: CHAN, LESLIE — GEORGIA INSTITUTE OF TECHNOLOGY
- Study coordinator: CHAN, LESLIE
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.