Creating quick tests for Lassa and other hemorrhagic fever viruses
Development of point-of-care testing for Lassa and other hemorrhagic fever arenaviruses
This study is working on creating quick and easy tests to help diagnose Lassa virus and similar illnesses, especially in remote areas where these viruses are common, so that people can get the care they need faster.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Duke University NIH-funded |
| Lab location | 1 site (Durham, United States) |
| Project ID | NIH-10877049 on NIH RePORTER |
What this research studies
This research focuses on developing point-of-care diagnostic tests for Lassa virus and other hemorrhagic fever arenaviruses, which are known to cause severe outbreaks with high mortality rates. The approach involves creating sensitive and broadly reactive antibody pairs that can quickly diagnose infections, particularly in remote areas where these viruses are endemic. By utilizing advanced techniques such as single chain antibody phage display libraries, the research aims to enhance current diagnostic capabilities and provide timely results for patients in affected regions.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals living in or traveling to regions where Lassa virus and other hemorrhagic fever viruses are prevalent.
Not a fit: Patients who do not reside in or have no exposure to areas affected by these viruses may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to faster and more accurate diagnosis of Lassa virus infections, potentially saving lives and improving outbreak management.
How similar studies have performed: Previous research has shown promise in developing rapid diagnostic tests for other infectious diseases, indicating that this approach could be successful.
Where this research is happening
Durham, United States
- Duke University — Durham, United States (Active)
Researchers
- Principal investigator: Gunn, Michael D — Duke University
- Study coordinator: Gunn, Michael D
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.