Creating Protective Antibodies for an HIV Vaccine

Induction of protective antibodies for HIV vaccine development

['FUNDING_OTHER'] · DUKE UNIVERSITY · NIH-11135439

This project aims to create a vaccine that helps the body make strong antibodies to protect against HIV.

Quick facts

Phase['FUNDING_OTHER']
Study typeNih_funding
SexAll
SponsorDUKE UNIVERSITY (nih funded)
Locations1 site (DURHAM, UNITED STATES)
Trial IDNIH-11135439 on ClinicalTrials.gov

What this research studies

This project is working to design an effective HIV vaccine for global use. Researchers are using advanced technologies and immunological tools to create a vaccine that teaches the body to produce special antibodies. These antibodies come in two main types: those that can broadly neutralize the virus and those that offer protection in other ways. The goal is to overcome past challenges and accelerate the creation of a vaccine that can prevent HIV infection.

Who could benefit from this research

Good fit: This research is foundational for anyone at risk of HIV infection who could benefit from a preventative vaccine in the future.

Not a fit: Patients already living with HIV would not directly benefit from a preventative vaccine, though related research might inform treatments.

Why it matters

Potential benefit: If successful, this work could lead to a highly effective vaccine that prevents HIV infection worldwide.

How similar studies have performed: Previous years of work have clarified the path forward for a protective HIV vaccine, building on defined roadblocks and first-generation immunogens.

Where this research is happening

DURHAM, UNITED STATES

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.

View on NIH RePORTER →

Conditions: Acquired Immune Deficiency Syndrome Virus, Acquired Immunodeficiency Syndrome Virus

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.