Creating personalized thresholds to better predict fractures in minority women
Official title: Does Creating Person-specific Precision Thresholds Enhance the Ability of a Single Bone Density Measure to Predict Fractures in Minority Women?
Funded at Ohio State University · NIH-10989941 · Data updated 2026-11-12
This study is looking to create personalized bone density guidelines for women, especially those from minority backgrounds, so that everyone gets the best care possible and their risk of fractures is more accurately understood.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Ohio State University NIH-funded |
| Lab location | 1 site (Columbus, UNITED STATES) |
| Project start | December 1, 2023 |
| Project end | November 30, 2027 |
| Funding year | 2025 |
| Award (this year) | $552,472 |
| NIH project number | 5R01AG080017-02 |
| Project ID | NIH-10989941 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are minority women who are at risk for bone fractures, particularly those who may not benefit from traditional bone density assessments.
✕Less likely to help
Patients who are not minority women or those who do not have concerns related to bone health may not receive benefits from this research.
What this research studies
This research aims to develop personalized thresholds for bone density measurements that take into account individual genetic and biological differences, particularly in minority women. By moving away from traditional one-size-fits-all thresholds that have been primarily based on Caucasian populations, the study seeks to reduce healthcare disparities in fracture risk assessment. The approach involves analyzing a diverse cohort to create more accurate predictions of fracture risk tailored to each individual's characteristics. This innovative method could lead to improved clinical practices and better health outcomes for underrepresented populations.
Why it matters
Potential benefit: If successful, this research could lead to more accurate fracture risk assessments and improved healthcare outcomes for minority women.
How similar studies have gone: Other research has shown that personalized approaches in healthcare can significantly improve outcomes, suggesting that this method could be effective as well.
Where this research is happening
-
Ohio State University
Columbus, United States Active
Researchers
- Principal investigator: Wu, Qing — Ohio State University
- Study coordinator: Wu, Qing
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.