Creating personalized models to improve hand function after injury or disease

A Transfer Learning Framework for Creating Subject-Specific Musculoskeletal Models of the Hand

['FUNDING_R21'] · UNIVERSITY OF FLORIDA · NIH-10040078

This study is looking at how everyone's unique hand structure affects how well they can use their hands, especially for people with conditions like stroke, arthritis, or amputation, so that we can create personalized treatments to help improve their hand function and overall quality of life.

Quick facts

Phase['FUNDING_R21']
Study typeNih_funding
SexAll
SponsorUNIVERSITY OF FLORIDA (nih funded)
Locations1 site (GAINESVILLE, UNITED STATES)
Trial IDNIH-10040078 on ClinicalTrials.gov

What this research studies

This research investigates how individual differences in anatomy and biomechanics affect hand function, particularly for patients with conditions like stroke, osteoarthritis, or amputation. By collecting detailed datasets on hand mechanics and muscle activity, the study aims to develop personalized models that can predict how changes in the hand's structure influence its ability to produce force. This approach will help tailor treatments and rehabilitation strategies to better meet the needs of each patient, ultimately improving their hand function and quality of life.

Who could benefit from this research

Good fit: Ideal candidates for this research include adults over 21 years old who have experienced hand function loss due to conditions like stroke, osteoarthritis, or traumatic injuries.

Not a fit: Patients with hand function intact or those under 21 years old may not receive benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to more effective, personalized rehabilitation strategies for individuals with hand impairments.

How similar studies have performed: Other research has shown promise in using personalized biomechanical models to improve treatment outcomes, indicating that this approach could be effective.

Where this research is happening

GAINESVILLE, UNITED STATES

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.

View on NIH RePORTER →

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.