Creating personalized 3D-printed vaginal tissue for reconstruction
Official title: Production of 3D Bioprinted Autologous Vaginal Tissue Constructs for Reconstructive Applications
Funded at Wake Forest University Health Sciences · NIH-11083075 · Data updated 2026-11-12
This study is exploring a new way to create personalized vaginal tissue using 3D printing and your own cells, which could help improve surgeries for people with vaginal abnormalities.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Wake Forest University Health Sciences NIH-funded |
| Lab location | 1 site (Winston-Salem, United States) |
| Project start | June 10, 2023 |
| Project end | March 31, 2028 |
| Funding year | 2025 |
| Award (this year) | $616,461 |
| NIH project number | 5R01HD112028-03 |
| Project ID | NIH-11083075 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research include individuals with congenital or acquired vaginal abnormalities requiring reconstructive surgery.
✕Less likely to help
Patients who do not have vaginal abnormalities or those who are not candidates for reconstructive surgery may not benefit from this research.
What this research studies
This research focuses on developing 3D bioprinted vaginal tissue constructs that are made from a patient's own cells, which can be used for reconstructive surgeries. The approach utilizes advanced tissue engineering techniques to create personalized tissue that matches the patient's anatomical needs. By using 3D printing technology, the researchers aim to produce these constructs with high precision and reproducibility, addressing the challenges faced in traditional tissue reconstruction methods. This innovative method seeks to improve the outcomes of surgeries for patients with congenital or acquired vaginal abnormalities.
Why it matters
Potential benefit: If successful, this research could provide patients with safer and more effective reconstructive options that utilize their own biological materials.
How similar studies have gone: Previous research has shown promise in using bioengineered tissues for various applications, indicating that this approach could be successful.
Where this research is happening
-
Wake Forest University Health Sciences
Winston-Salem, United States Active
Researchers
- Principal investigator: Yoo, James J — Wake Forest University Health Sciences
- Study coordinator: Yoo, James J
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.