Creating personalized 3D models to improve cancer treatment safety

Development and application of whole-body patient-specific computational mesh phantoms for organ dosimetry and second primary cancer risk quantification following external beam radiotherapy

NIH-funded research University of Florida · NIH-10996673

This study is working on creating personalized 3D models of your body to make radiation therapy for cancer safer and more effective, helping to protect your healthy organs while treating the cancer.

Quick facts

Grant typeFellowship grant
Study typeNIH-funded research
Funding institutionUniversity of Florida NIH-funded
Lab location1 site (Gainesville, United States)
Project IDNIH-10996673 on NIH RePORTER

What this research studies

This research focuses on developing advanced 3D computational models that represent individual patients' bodies to enhance the safety of external beam radiotherapy for cancer treatment. By using detailed anatomical information, these models aim to accurately calculate radiation doses to organs at risk, which can help in minimizing the chances of developing second primary cancers after treatment. The approach involves integrating patient-specific data into sophisticated simulations that predict how radiation affects various body tissues. This could lead to more tailored and effective treatment plans for cancer patients.

Who could benefit from this research

Good fit: Ideal candidates for this research include cancer patients of all ages who are scheduled to receive external beam radiotherapy.

Not a fit: Patients who are not undergoing radiotherapy or those with conditions that do not require radiation treatment may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could significantly reduce the risk of secondary cancers in patients undergoing radiotherapy.

How similar studies have performed: Previous research has shown promise in using computational phantoms for radiation dose calculations, indicating that this approach could be effective.

Where this research is happening

Gainesville, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.