Creating personalized 3D models to improve cancer treatment safety
Official title: Development and application of whole-body patient-specific computational mesh phantoms for organ dosimetry and second primary cancer risk quantification following external beam radiotherapy
Funded at University of Florida · NIH-10996673 · Data updated 2026-11-12
This study is working on creating personalized 3D models of your body to make radiation therapy for cancer safer and more effective, helping to protect your healthy organs while treating the cancer.
Quick facts
| Grant type | Fellowship grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Florida NIH-funded |
| Lab location | 1 site (Gainesville, United States) |
| Project start | August 16, 2024 |
| Project end | August 15, 2027 |
| Funding year | 2024 |
| Award (this year) | $43,902 |
| NIH project number | 1F31CA288051-01A1 |
| Project ID | NIH-10996673 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research include cancer patients of all ages who are scheduled to receive external beam radiotherapy.
✕Less likely to help
Patients who are not undergoing radiotherapy or those with conditions that do not require radiation treatment may not benefit from this research.
What this research studies
This research focuses on developing advanced 3D computational models that represent individual patients' bodies to enhance the safety of external beam radiotherapy for cancer treatment. By using detailed anatomical information, these models aim to accurately calculate radiation doses to organs at risk, which can help in minimizing the chances of developing second primary cancers after treatment. The approach involves integrating patient-specific data into sophisticated simulations that predict how radiation affects various body tissues. This could lead to more tailored and effective treatment plans for cancer patients.
Why it matters
Potential benefit: If successful, this research could significantly reduce the risk of secondary cancers in patients undergoing radiotherapy.
How similar studies have gone: Previous research has shown promise in using computational phantoms for radiation dose calculations, indicating that this approach could be effective.
Where this research is happening
-
University of Florida
Gainesville, United States Active
Researchers
- Principal investigator: Dawson, Robert Joseph — University of Florida
- Study coordinator: Dawson, Robert Joseph
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.