Creating patient-specific tumor models for cancer treatment
Official title: CELL EXPANSION BIOREACTORS FOR ASSAY-READY IMMUNOCOMPETENT PATIENT MODELS
Funded at Link Biosystems INC. · NIH-11280484 · Data updated 2026-11-12
This study is working on creating special systems that grow human tumor cells like they would in the body, so doctors can test different cancer treatments on them and find the best options for each patient.
Quick facts
| Grant type | Sbir 2 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Link Biosystems INC. NIH-funded |
| Lab location | 1 site (Irvington, United States) |
| Project start | August 1, 2023 |
| Project end | January 1, 2027 |
| Funding year | 2025 |
| Award (this year) | $911,110 |
| NIH project number | 4R44CA281356-02 |
| Project ID | NIH-11280484 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are patients with various types of cancer, especially those with rare cancers or those who have previously banked tumor samples.
✕Less likely to help
Patients who do not have cancer or those whose tumors cannot be biobanked may not benefit from this research.
What this research studies
This research focuses on developing advanced bioreactors that can grow human tumor cells in a way that mimics the natural environment of the body. By using these models, researchers aim to better understand how different cancer treatments work for individual patients. The approach involves using patient tumor samples to create identical tumor tissues that can be tested with various drugs, including immunotherapies. This could lead to more effective and personalized cancer treatment options for patients.
Why it matters
Potential benefit: If successful, this research could lead to more effective and personalized cancer treatments tailored to individual patient needs.
How similar studies have gone: Other research has shown promise in using similar bioreactor approaches to create patient-specific models, indicating potential for success in this area.
Where this research is happening
-
Link Biosystems INC.
Irvington, United States Active
Researchers
- Principal investigator: Ronaldson, Kacey — Link Biosystems INC.
- Study coordinator: Ronaldson, Kacey
Related research
Other NIH-funded projects on the same topics.
-
Cell Expansion Bioreactors for Patient-Specific Tumor Models
A project to grow patient tumor cells in a special bioreactor to create ready-to-use tumor models for testing cancer drugs.
-
Improving the production of patient-specific stem cells for therapy
This study is working on a better way to grow special stem cells that can be used in personalized treatments for patients, making it easier and more affordable to produce the large amounts needed for therapy.
-
Improving the production of heart cells from stem cells for better treatments.
This study is working on a better way to grow heart cells from stem cells, which can help doctors understand and treat heart diseases more effectively, making it easier to use these cells in patient care.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.