Creating patient-derived tumor models from common cancers

PDX Panels from Common Tumors

NIH-funded research Leidos Biomedical Research, INC. · NIH-10937056

This study is looking for patients to share their tumor samples so researchers can grow them in mice and learn how different tumors behave and respond to treatments, helping to create more personalized cancer therapies just for you.

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionLeidos Biomedical Research, INC. NIH-funded
Lab location1 site (Frederick, United States)
Project IDNIH-10937056 on NIH RePORTER

What this research studies

This research focuses on developing patient-derived xenograft (PDX) panels from common tumors, which involves taking tumor samples from patients and implanting them into mice to study their behavior and response to treatments. By creating these models, researchers aim to better understand how different tumors grow and respond to various therapies. This approach allows for personalized medicine, where treatments can be tailored based on the specific characteristics of a patient's tumor. Patients may have the opportunity to contribute their tumor samples to help advance cancer research and treatment options.

Who could benefit from this research

Good fit: Ideal candidates for participation are patients diagnosed with common tumors who are undergoing treatment or have tumor samples available.

Not a fit: Patients with rare tumors or those who do not have accessible tumor samples may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to more effective and personalized treatment options for patients with common tumors.

How similar studies have performed: Other research has shown success in using patient-derived xenograft models to improve cancer treatment strategies, indicating a promising approach.

Where this research is happening

Frederick, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.