Creating patient-derived cancer models to improve health equity.
Official title: Administrative Core
Funded at Virginia Commonwealth University · NIH-10890846 · Data updated 2026-11-12
This study is working to create special models from tumor samples of underrepresented minority patients with various types of cancer, like breast and lung cancer, to help us understand and improve treatment for everyone affected by these diseases.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Virginia Commonwealth University NIH-funded |
| Lab location | 1 site (Richmond, United States) |
| Project start | July 19, 2023 |
| Project end | June 30, 2028 |
| Funding year | 2024 |
| Award (this year) | $91,701 |
| NIH project number | 5U54CA283762-02 |
| Project ID | NIH-10890846 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research include underrepresented minority patients diagnosed with specific types of cancer, such as breast or pancreatic cancer.
✕Less likely to help
Patients with cancers not included in the study, or those who do not belong to underrepresented minority groups, may not benefit from this research.
What this research studies
This research focuses on developing patient-derived xenografts (PDX) and organoids (PDO) from underrepresented minority tumor samples, particularly for cancers such as breast, pancreatic, genitourinary, gynecologic, lung, and gastrointestinal malignancies. The project aims to enhance cancer treatment and research by utilizing these models to better understand cancer disparities and improve patient outcomes. The initiative is supported by a collaborative team at Virginia Commonwealth University, which includes experts in clinical oncology and cancer prevention, ensuring a comprehensive approach to addressing health disparities. The Administrative Core will oversee the project's progress and facilitate communication among stakeholders.
Why it matters
Potential benefit: If successful, this research could lead to more effective and equitable cancer treatments tailored to underrepresented populations.
How similar studies have gone: Previous research has shown success in using patient-derived models to study cancer, indicating a promising approach for addressing health disparities.
Where this research is happening
-
Virginia Commonwealth University
Richmond, United States Active
Researchers
- Principal investigator: Trevino, Jose G. — Virginia Commonwealth University
- Study coordinator: Trevino, Jose G.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.