Creating new ways to measure movement in ataxia-telangiectasia
Official title: Development of real-world motor outcome measures in ataxia-telangiectasia
Funded at Massachusetts General Hospital · NIH-11001141 · Data updated 2026-11-12
This study is looking to improve how we track movement in people with ataxia-telangiectasia (A-T) by using wearable sensors that can gather information about your daily activities at home, helping doctors better understand your symptoms and how the condition changes over time.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Massachusetts General Hospital NIH-funded |
| Lab location | 1 site (Boston, United States) |
| Project start | December 15, 2023 |
| Project end | November 30, 2028 |
| Funding year | 2025 |
| Award (this year) | $584,256 |
| NIH project number | 5R01NS134597-02 |
| Project ID | NIH-11001141 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research include individuals diagnosed with ataxia-telangiectasia, ranging from children to adults.
✕Less likely to help
Patients without a diagnosis of ataxia-telangiectasia or those with other unrelated neurological conditions may not benefit from this research.
What this research studies
This research focuses on developing sensitive and meaningful assessments of motor function in individuals with ataxia-telangiectasia (A-T) using wearable sensors. By collecting movement data continuously at home, the study aims to capture daily fluctuations in symptoms and provide real-time information about disease status. The approach utilizes advanced algorithms and machine learning to analyze data from wrist or ankle sensors, which can help in understanding disease progression and support clinical care and drug development.
Why it matters
Potential benefit: If successful, this research could lead to improved monitoring of disease severity and better-informed treatment decisions for patients with ataxia-telangiectasia.
How similar studies have gone: Other research has shown promise in using wearable technology for monitoring movement in neurological disorders, indicating that this approach could be effective.
Where this research is happening
-
Massachusetts General Hospital
Boston, United States Active
Researchers
- Principal investigator: Gupta, Anoopum Satyawan — Massachusetts General Hospital
- Study coordinator: Gupta, Anoopum Satyawan
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.