Creating new vaccine strategies to improve immunity against influenza
Official title: Computationally designed anchor scaffolds for elicitation of broadly neutralizing influenza antibodies
Funded at Florida State University · NIH-10845655 · Data updated 2026-11-12
This study is exploring new ways to make flu vaccines even better by creating special tools that help your body fight off the virus more effectively, aiming to give you stronger and longer-lasting protection against the flu.
Quick facts
| Grant type | R21 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Florida State University NIH-funded |
| Lab location | 1 site (Tallahassee, United States) |
| Project start | May 22, 2023 |
| Project end | April 30, 2026 |
| Funding year | 2024 |
| Award (this year) | $156,393 |
| NIH project number | 5R21AI178556-03 |
| Project ID | NIH-10845655 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research include individuals who are at high risk for influenza, such as the elderly, young children, and those with compromised immune systems.
✕Less likely to help
Patients who are not at risk for influenza or those who have already received a recent influenza vaccine may not benefit from this research.
What this research studies
This research focuses on enhancing the immune response to influenza viruses by developing innovative vaccine strategies. The team aims to design anchor scaffolds that can elicit broadly neutralizing antibodies against the influenza virus, specifically targeting conserved regions of the virus that are less likely to mutate. By using computational methods to create these scaffolds, the researchers hope to improve the effectiveness of vaccines and provide longer-lasting protection against influenza. The study will involve testing these scaffolds in combination with existing vaccine components to determine their ability to boost the immune response.
Why it matters
Potential benefit: If successful, this research could lead to more effective influenza vaccines that provide broader and longer-lasting protection against various strains of the virus.
How similar studies have gone: Other research has shown promise in developing vaccines that target conserved viral epitopes, indicating that this approach has potential for success.
Where this research is happening
-
Florida State University
Tallahassee, United States Active
Researchers
- Principal investigator: Mousa, Jarrod — Florida State University
- Study coordinator: Mousa, Jarrod
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.