Creating new treatments for idiopathic lung fibrosis
Modeling to Design Treatments for Idiopathic Lung Fibrosis
This study is looking at idiopathic pulmonary fibrosis (IPF) to find out which cells in the lungs cause the disease and how we can stop them from making things worse, with the hope of creating better treatments for people living with IPF.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Virginia NIH-funded |
| Lab location | 1 site (Charlottesville, United States) |
| Project ID | NIH-10871896 on NIH RePORTER |
What this research studies
This research focuses on understanding idiopathic pulmonary fibrosis (IPF), a severe lung disease that leads to progressive scarring of lung tissue. The team aims to identify the cells that contribute to the disease and how they can be targeted to stop or reverse the damage. By combining computational modeling with laboratory experiments, they will explore how certain cells in the lungs transform and how this process can be interrupted. The ultimate goal is to develop new treatment strategies that could improve outcomes for patients with IPF.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals diagnosed with idiopathic pulmonary fibrosis who are seeking new treatment options.
Not a fit: Patients with other forms of lung disease or those who do not have idiopathic pulmonary fibrosis may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new therapies that halt or even reverse the progression of idiopathic pulmonary fibrosis.
How similar studies have performed: Previous research has shown promise in using computational modeling and cellular analysis to develop treatments for similar fibrotic diseases, indicating a potential for success in this approach.
Where this research is happening
Charlottesville, United States
- University of Virginia — Charlottesville, United States (Active)
Researchers
- Principal investigator: Peirce-Cottler, Shayn — University of Virginia
- Study coordinator: Peirce-Cottler, Shayn
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.