Creating new treatments for gonorrhea infections

Development of novel anti-Neisseria gonorrhoeae therapeutic agents

NIH-funded research Purdue University · NIH-10884442

This study is looking for new ways to treat gonorrhea, especially since some antibiotics aren't working anymore, and it might help patients by finding better treatments using existing medications that show promise against the infection.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionPurdue University NIH-funded
Lab location1 site (West Lafayette, United States)
Project IDNIH-10884442 on NIH RePORTER

What this research studies

This research focuses on developing new therapeutic agents to combat gonorrhea, a sexually transmitted infection caused by the bacteria Neisseria gonorrhoeae. The project aims to identify novel targets and molecules that can effectively treat infections, especially in light of increasing antibiotic resistance. The researchers are exploring FDA-approved carbonic anhydrase inhibitors, which have shown promising antimicrobial activity against this pathogen. Patients may benefit from innovative treatments that could address the growing challenge of antibiotic-resistant gonorrhea.

Who could benefit from this research

Good fit: Ideal candidates for this research include individuals diagnosed with gonorrhea or those at high risk of infection.

Not a fit: Patients who are not sexually active or those who have not been diagnosed with gonorrhea may not receive any benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to effective new treatments for gonorrhea, reducing complications such as infertility and pelvic inflammatory disease.

How similar studies have performed: Previous research has shown promise in using carbonic anhydrase inhibitors for antimicrobial purposes, indicating potential success for this novel approach.

Where this research is happening

West Lafayette, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.