Creating new treatments for giardiasis and cryptosporidiosis
Development of dual effective kinase inhibitors as syndromic treatment of Giardiasis and Cryptosporidiosis
This study is looking for a new treatment that can help people, especially those with weakened immune systems and malnourished kids, who are suffering from giardiasis and cryptosporidiosis, two infections that cause bad diarrhea.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Washington NIH-funded |
| Lab location | 1 site (Seattle, United States) |
| Project ID | NIH-11013299 on NIH RePORTER |
What this research studies
This research focuses on developing a single effective therapy for giardiasis and cryptosporidiosis, two parasitic infections that can cause severe diarrhea, particularly in immunocompromised patients and malnourished children. The approach involves identifying and testing dual effective kinase inhibitors that target the parasites responsible for these infections. By screening various chemical compounds, the researchers aim to find a treatment that can be used even when diagnosis is uncertain or delayed, potentially benefiting patients with asymptomatic cases as well.
Who could benefit from this research
Good fit: Ideal candidates for this research are children under 11 years old and immunocompromised individuals who are at risk for these infections.
Not a fit: Patients who do not have giardiasis or cryptosporidiosis, or those who are not within the specified age range, may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could provide a much-needed effective treatment option for patients suffering from giardiasis and cryptosporidiosis.
How similar studies have performed: Other research has shown promise in developing kinase inhibitors for treating parasitic infections, suggesting that this approach could be effective.
Where this research is happening
Seattle, United States
- University of Washington — Seattle, United States (Active)
Researchers
- Principal investigator: Ojo, Kayode K — University of Washington
- Study coordinator: Ojo, Kayode K
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.