Creating new treatments for asthma using modified lung proteins
Development of SP-A Derived Peptidomimetics for the Treatment of Asthma - Phase II
This study is exploring new treatments for asthma by creating tiny molecules that act like a natural lung protein to help relax the airways and prevent asthma attacks, aiming to offer a better option for people living with this condition.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Raesedo, LLC NIH-funded |
| Lab location | 1 site (Tucson, United States) |
| Project ID | NIH-10708853 on NIH RePORTER |
What this research studies
This research focuses on developing new therapies for asthma by creating small molecules that mimic a natural lung protein called Surfactant Protein A (SP-A). These modified proteins aim to reduce airway constriction and prevent asthma exacerbations, which can lead to serious health issues. The approach involves engineering these molecules to enhance their stability and effectiveness when delivered to the lungs. By targeting the underlying inflammation in asthma, this research seeks to provide a novel treatment option for patients suffering from this condition.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals with moderate to severe asthma who experience frequent exacerbations.
Not a fit: Patients with mild asthma or those who do not experience exacerbations may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to more effective treatments for asthma, reducing the frequency and severity of exacerbations.
How similar studies have performed: While the approach of using modified proteins for asthma treatment is innovative, similar strategies targeting lung inflammation have shown promise in other studies.
Where this research is happening
Tucson, United States
- Raesedo, LLC — Tucson, United States (Active)
Researchers
- Principal investigator: Ledford, Julie Gunnells — Raesedo, LLC
- Study coordinator: Ledford, Julie Gunnells
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.