Creating new treatments for aggressive brain tumors.
Development of Small Molecule Inhibitors and Biologic Agents for Treatment of Glioblastoma Using Intracerebral Microdialysis and Signatures of Vulnerability
This study is looking for new and better treatments for glioblastoma, a tough type of brain tumor, to help adult patients by testing different therapies that could work better than what we have now.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Beckman Research Institute/city of Hope NIH-funded |
| Lab location | 1 site (Duarte, United States) |
| Project ID | NIH-10928754 on NIH RePORTER |
What this research studies
This research focuses on developing innovative therapies for glioblastoma, a highly aggressive brain tumor. The team will explore various approaches, including small molecule inhibitors and biologic agents, to overcome challenges such as tumor heterogeneity and the blood-brain barrier. Patients may benefit from new treatment options that are designed to be more effective than current therapies. The research will involve translating findings from laboratory studies into early-stage clinical trials for adult patients.
Who could benefit from this research
Good fit: Ideal candidates for this research are adults diagnosed with glioblastoma who are seeking new treatment options.
Not a fit: Patients with other types of brain tumors or those who are not diagnosed with glioblastoma may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to more effective treatments for glioblastoma, potentially improving survival rates and quality of life for patients.
How similar studies have performed: Previous research has shown promise in developing targeted therapies for glioblastoma, indicating potential for success with similar approaches in this study.
Where this research is happening
Duarte, United States
- Beckman Research Institute/city of Hope — Duarte, United States (Active)
Researchers
- Principal investigator: Portnow, Jana — Beckman Research Institute/city of Hope
- Study coordinator: Portnow, Jana
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.