Creating new tools for purifying proteins from blood plasma
Official title: Development of Custom nanoCLAMP Affinity Chromatography Resins for Fast, Efficient Purification of Plasma Proteins
Funded at Nectagen, INC. · NIH-11006459 · Data updated 2026-11-12
This study is working on a new way to clean and gather important proteins from blood plasma, which could help make treatments more affordable and improve how we create therapies for patients.
Quick facts
| Grant type | Sbir 1 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Nectagen, INC. NIH-funded |
| Lab location | 1 site (Lawrence, UNITED STATES) |
| Project start | July 1, 2024 |
| Project end | June 30, 2025 |
| Funding year | 2024 |
| Award (this year) | $275,000 |
| NIH project number | 1R43TR005370-01 |
| Project ID | NIH-11006459 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for benefiting from this research include individuals requiring plasma-derived therapies for conditions like von Willebrand disease or other blood coagulation disorders.
✕Less likely to help
Patients with conditions that do not involve plasma-derived therapies or those who do not require protein purification may not benefit from this research.
What this research studies
This research focuses on developing advanced nanoCLAMP affinity chromatography resins that can efficiently purify proteins from blood plasma. By creating a more effective method for recovering these proteins, the project aims to lower the costs associated with producing plasma-derived therapies. The approach involves identifying and characterizing specific nanoCLAMPs that can bind to important therapeutic proteins, thereby enhancing the purification process. This could lead to improved production methods for existing treatments and facilitate the development of new therapies.
Why it matters
Potential benefit: If successful, this research could lead to more affordable and accessible plasma-based therapies for patients.
How similar studies have gone: Other research has shown promise in developing affinity chromatography techniques, indicating that this approach could lead to significant advancements in protein purification.
Where this research is happening
-
Nectagen, INC.
Lawrence, United States Active
Researchers
- Principal investigator: Suderman, Richard John — Nectagen, INC.
- Study coordinator: Suderman, Richard John
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.