Creating new technology to analyze and separate HDL particles
Development of a Novel Technology for Preparative Fractionation and Characterization of Lipoprotein Particles
This study is exploring a new way to better understand good cholesterol (HDL) in order to find new treatments that could help improve health for people with different health issues.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of California at Davis NIH-funded |
| Lab location | 1 site (Davis, United States) |
| Project ID | NIH-10892830 on NIH RePORTER |
What this research studies
This research focuses on developing a novel technology to better isolate and characterize high-density lipoproteins (HDL), which are crucial for maintaining health and longevity. The approach involves using advanced size exclusion chromatography combined with multiple optical detectors to accurately measure HDL particle size and quantity. By improving our understanding of HDL, the research aims to uncover new therapeutic strategies to enhance HDL function, potentially leading to better health outcomes for patients with various diseases.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals at risk for cardiovascular diseases or those with existing conditions related to HDL dysfunction.
Not a fit: Patients with conditions unrelated to HDL or those who do not have cardiovascular risk factors may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved therapies for cardiovascular diseases and other conditions linked to HDL dysfunction.
How similar studies have performed: Previous research has shown promise in HDL characterization, but this approach is innovative and aims to overcome existing technological barriers.
Where this research is happening
Davis, United States
- University of California at Davis — Davis, United States (Active)
Researchers
- Principal investigator: Zivkovic, Angela M — University of California at Davis
- Study coordinator: Zivkovic, Angela M
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.