NIH-funded research NIH-funded research

Creating new technologies to improve cancer treatment through gene modification.

Official title: Development of New Technologies at Roswell Park to Further Cancer-Based Research and Treatment Through Genome Modification

Funded at Roswell Park Cancer Institute Corp · NIH-10931670 · Data updated 2026-11-12

This study is exploring new ways to change genes to improve cancer treatments, and it's for anyone affected by cancer who hopes for better therapies in the future.

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionRoswell Park Cancer Institute Corp
NIH-funded
Lab location1 site (Buffalo, United States)
Project startSeptember 19, 2023
Project endAugust 31, 2028
Funding year2024
Award (this year)$324,868
NIH project number5R50CA283761-02
Project IDNIH-10931670 on NIH RePORTER

Who could benefit from this research

Could help

Ideal candidates for participation or benefit from this research are individuals diagnosed with cancer who may be eligible for novel gene-targeted therapies.

Less likely to help

Patients with non-cancerous conditions or those who do not meet the criteria for gene-targeted therapies may not receive benefits from this research.

What this research studies

This research focuses on advancing cancer treatment by developing new technologies for genome modification. Led by Dr. Aimee Stablewski at Roswell Park Comprehensive Cancer Center, the project aims to enhance the capabilities of gene targeting and transgenic resources. By collaborating with various cancer researchers, the team will apply innovative genome editing techniques to better understand and treat different types of cancer. Patients may benefit from the insights gained through these advanced methodologies in future therapies.

Why it matters

Potential benefit: If successful, this research could lead to more effective cancer treatments tailored to individual genetic profiles.

How similar studies have gone: Previous research in genome modification for cancer treatment has shown promising results, indicating that this approach has the potential for significant advancements.

Where this research is happening

  • Roswell Park Cancer Institute Corp
    Buffalo, United States
    Active

Researchers

  • Principal investigator: Stablewski, Aimee B — Roswell Park Cancer Institute Corp
  • Study coordinator: Stablewski, Aimee B

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About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.