Creating new technologies to better manage pain and opioid use during surgery

Developing novel technologies to monitor nociception and opioid administration during surgery and general anesthesia in order to minimize post-operative opioid requirements

NIH-funded research Pascall Systems, Incorporated · NIH-10875550

This study is looking at new ways to track how much pain you feel during surgery and how much medicine you need to feel better, with the hope of making sure you get just the right amount of pain relief and reducing the chances of needing opioids later on.

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionPascall Systems, Incorporated NIH-funded
Lab location1 site (Boston, UNITED STATES)
Project IDNIH-10875550 on NIH RePORTER

What this research studies

This research focuses on developing advanced technologies to monitor pain responses and opioid administration during surgical procedures and anesthesia. By utilizing innovative sensors and algorithms, the project aims to create a more accurate measure of pain control, which can lead to better management of opioid use. The goal is to reduce postoperative pain and the risk of chronic opioid dependency by ensuring that patients receive the appropriate amount of pain relief during surgery. This approach involves analyzing autonomic and neurophysiological markers to improve the effectiveness of pain management strategies.

Who could benefit from this research

Good fit: Ideal candidates for this research are surgical patients who are undergoing procedures requiring general anesthesia and may benefit from improved pain management.

Not a fit: Patients who are not undergoing surgery or those who do not require anesthesia will likely not benefit from this research.

Why it matters

Potential benefit: If successful, this research could significantly reduce postoperative pain and lower the need for opioids, thereby decreasing the risk of opioid dependency in surgical patients.

How similar studies have performed: While the approach of integrating advanced monitoring technologies is innovative, similar research has shown promise in improving pain management and reducing opioid use in surgical settings.

Where this research is happening

Boston, UNITED STATES

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.