NIH-funded research NIH-funded research

Creating new resources to improve understanding and treatment of Myelodysplastic Syndrome (MDS)

Official title: Development of Innovative Resources to Advance MDS Research

Funded at Fred Hutchinson Cancer Center · NIH-10925153 · Data updated 2026-11-12

This study is all about understanding Myelodysplastic Syndrome (MDS) better by creating helpful resources for researchers, like a map of the mutations that cause MDS and patient stem cell lines, so that we can find better treatments for people living with this condition.

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionFred Hutchinson Cancer Center
NIH-funded
Lab location1 site (Seattle, United States)
Project startSeptember 15, 2023
Project endJuly 31, 2028
Funding year2024
Award (this year)$1,511,993
NIH project number5RC2DK127989-02
Project IDNIH-10925153 on NIH RePORTER

Who could benefit from this research

Could help

Ideal candidates for this research are individuals diagnosed with Myelodysplastic Syndrome or those at risk of developing it.

Less likely to help

Patients with other types of blood disorders that are not related to MDS may not benefit from this research.

What this research studies

This research focuses on Myelodysplastic Syndrome (MDS), a group of blood disorders caused by mutations in blood stem cells. The project aims to develop essential resources for researchers, including a detailed map of MDS mutations, a collection of stem cell lines derived from patients, and information on how MDS responds to various drugs. By creating these tools, the research seeks to enhance the understanding of MDS biology and improve treatment options for patients. The approach includes both laboratory work and the compilation of clinical data to inform future therapies.

Why it matters

Potential benefit: If successful, this research could lead to better-targeted therapies and improved outcomes for patients with MDS.

How similar studies have gone: Previous research has shown promise in developing targeted therapies for blood disorders, indicating potential success for this innovative approach.

Where this research is happening

  • Fred Hutchinson Cancer Center
    Seattle, United States
    Active

Researchers

  • Principal investigator: Bleakley, Marie — Fred Hutchinson Cancer Center
  • Study coordinator: Bleakley, Marie

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.