Creating new prostate cancer cell lines to help Black men
Official title: Novel Prostate Cancer Cell Lines to Address Prostate Cancer Disparity in Black Men
Funded at University of the West Indies · NIH-10889202 · Data updated 2026-11-12
This study is working to create new prostate cancer cell lines that better represent the unique traits of prostate cancer in men of African ancestry, so researchers can learn more about how the disease behaves in this group and see how well different treatments work for them.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of the West Indies NIH-funded |
| Lab location | 1 site (Kingston, Jamaica) |
| Project start | August 10, 2020 |
| Project end | July 31, 2025 |
| Funding year | 2024 |
| Award (this year) | $122,933 |
| NIH project number | 5K43TW011387-05 |
| Project ID | NIH-10889202 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are men of African ancestry who are diagnosed with prostate cancer.
✕Less likely to help
Patients of non-African ancestry may not receive direct benefits from this research.
What this research studies
This research aims to develop new prostate cancer cell lines that reflect the unique characteristics of prostate cancer in men of African ancestry. By creating these cell lines, the researchers hope to better understand how prostate cancer behaves in this population and to evaluate the effectiveness of various chemotherapy drugs and natural compounds. The study will involve characterizing the new cell lines and comparing their responses to treatments with existing cell lines derived from men of European ancestry. This approach addresses the significant health disparities faced by men of African ancestry in terms of prostate cancer incidence and mortality.
Why it matters
Potential benefit: If successful, this research could lead to more effective treatments for prostate cancer specifically tailored for Black men.
How similar studies have gone: While there has been limited research specifically targeting prostate cancer disparities in Black men, the approach of developing ancestry-specific cell lines has shown promise in other cancer types.
Where this research is happening
-
University of the West Indies
Kingston, Jamaica Active
Researchers
- Principal investigator: Badal, Simone Annmarie — University of the West Indies
- Study coordinator: Badal, Simone Annmarie
Related research
Other NIH-funded projects on the same topics.
-
Cardiovascular risk planning and reduction for men with prostate cancer
A program to better predict and reduce heart disease risk in men treated for prostate cancer, especially older patients.
-
Effects of ADT on motivation and emotion in prostate cancer patients
This project looks at how androgen deprivation therapy may affect motivation and mood over time in men with prostate cancer.
-
Causal Protein Markers to Understand and Predict Prostate Cancer Risk in Africans and Europeans
A cancer research project looking at proteins linked to prostate cancer to better understand why it happens and how risk differs between African and European populations.
-
Ethical multimodal AI platform to improve prostate cancer detection with ultrasound
A patient-friendly AI system uses ultrasound and MRI information to help doctors better find prostate cancer, aiming to improve accuracy and access.
-
Characterizing epigenetic targets in prostate cancer to help AR-driven cancer
A research project at MD Anderson aims to understand how epigenetic factors shape androgen receptor signaling in prostate cancer to find new ways to treat resistant forms of the disease.
-
AR and RNA-binding in prostate cancer resistance
A cancer research grant exploring how the androgen receptor’s interaction with RNA may drive treatment resistance in prostate cancer, with potential to guide new therapies.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.