Creating new pain relief and mental health medications using specialized chemical reactions.
Official title: Rearrangement Reactions of Divinyldiaziridines for the Enantioselective Synthesis of Diazepines and Benzodiazepines - Supplemental for Equipment Purchase
Funded at Rowan University · NIH-11009708 · Data updated 2026-11-12
This study is looking at new ways to create special medicines called diazepines and benzodiazepines, which can help with pain and mental health issues, by experimenting with different methods to make them more effective and targeted for patients like you.
Quick facts
| Grant type | R15 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Rowan University NIH-funded |
| Lab location | 1 site (Glassboro, United States) |
| Project start | August 1, 2023 |
| Project end | July 31, 2026 |
| Funding year | 2024 |
| Award (this year) | $98,800 |
| NIH project number | 3R15GM151707-01S1 |
| Project ID | NIH-11009708 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are individuals suffering from chronic pain or mental health disorders who may benefit from new therapeutic options.
✕Less likely to help
Patients who are not experiencing pain or mental health issues may not receive any benefit from this research.
What this research studies
This research focuses on developing new methods to synthesize complex chemical compounds known as diazepines and benzodiazepines, which are important for treating pain and mental health disorders. The researchers will explore specific rearrangement reactions of divinyldiaziridines to create optically pure versions of these compounds. By systematically testing different reaction conditions, they aim to produce more effective and targeted medications. This work could lead to advancements in how we manage pain and psychiatric conditions.
Why it matters
Potential benefit: If successful, this research could lead to the development of more effective medications for pain relief and mental health treatment.
How similar studies have gone: While the specific rearrangement reactions being studied are novel, similar approaches in synthesizing complex drug compounds have shown promise in past research.
Where this research is happening
-
Rowan University
Glassboro, United States Active
Researchers
- Principal investigator: Moura-Letts, Gustavo — Rowan University
- Study coordinator: Moura-Letts, Gustavo
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.