Creating new methods to make important drug components.
Official title: Development of Strategies for the Synthesis of Heterocycles
Funded at University of Florida · NIH-11021029 · Data updated 2026-11-12
This study is looking for new and affordable ways to create important building blocks for medicines by changing common ingredients, which could help scientists discover new drugs to improve health.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Florida NIH-funded |
| Lab location | 1 site (Gainesville, United States) |
| Project start | May 1, 2023 |
| Project end | February 29, 2028 |
| Funding year | 2025 |
| Award (this year) | $357,345 |
| NIH project number | 5R35GM149246-03 |
| Project ID | NIH-11021029 on NIH RePORTER |
Who could benefit from this research
✓Could help
Patients who may benefit from this research are those in need of new pharmaceutical treatments for diseases that currently have limited options.
✕Less likely to help
Patients with conditions that are not addressed by heterocyclic compounds may not receive any benefit from this research.
What this research studies
This research focuses on developing innovative and cost-effective methods for synthesizing heterocycles, which are crucial components of many pharmaceutical drugs. By modifying readily available amines through a process called C–H bond functionalization, the project aims to create new compounds that could enhance drug discovery. The researchers will explore unique catalytic methods to efficiently produce these compounds, including new approaches that have not been widely used before. The goal is to generate new structural frameworks that could lead to the discovery of novel medications.
Why it matters
Potential benefit: If successful, this research could lead to the development of more effective and affordable medications for various health conditions.
How similar studies have gone: Previous research has shown promise in developing new synthetic methods for drug components, indicating that this approach could yield significant advancements.
Where this research is happening
-
University of Florida
Gainesville, United States Active
Researchers
- Principal investigator: Seidel, Daniel — University of Florida
- Study coordinator: Seidel, Daniel
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.