NIH-funded research Fellowship grant

Creating new methods to make amines from nitrogen

Official title: An Electrochemical Approach to Amine Synthesis from Nitrogen

Funded at California Institute of Technology · NIH-10914036 · Data updated 2026-11-12

This study is exploring new, easier ways to make important compounds for medications by using special materials that work better at lower temperatures, which could lead to better treatments for patients.

Quick facts

Grant typeFellowship grant
Study typeNIH-funded research
Funding institutionCalifornia Institute of Technology
NIH-funded
Lab location1 site (Pasadena, United States)
Project startAugust 9, 2023
Project endAugust 8, 2026
Funding year2024
Award (this year)$73,828
NIH project number5F32GM151784-02
Project IDNIH-10914036 on NIH RePORTER

Who could benefit from this research

Could help

Ideal candidates for benefiting from this research include individuals who rely on nitrogen-containing medications or treatments for their health conditions.

Less likely to help

Patients who do not use or require nitrogen-containing medications may not see direct benefits from this research.

What this research studies

This research focuses on developing innovative techniques to synthesize amines, which are important for many health-related small molecules. The project aims to improve upon traditional methods that require high temperatures and pressures by using advanced catalysts that operate under milder conditions. By studying natural nitrogen-fixing processes, the research seeks to create more efficient and environmentally friendly ways to produce ammonia and other nitrogen-containing compounds. Patients may benefit from new medications and treatments derived from these improved synthesis methods.

Why it matters

Potential benefit: If successful, this research could lead to more efficient production of essential medications and chemicals that contain nitrogen.

How similar studies have gone: While there have been successful approaches in nitrogen fixation, this specific method of synthesizing amines from nitrogen is relatively novel and untested.

Where this research is happening

  • California Institute of Technology
    Pasadena, United States
    Active

Researchers

  • Principal investigator: Ovian, John Michael — California Institute of Technology
  • Study coordinator: Ovian, John Michael

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.