Creating new methods to build important sugar molecules for health
Official title: Development of Catalytic Glycosylations and Biologically Important Glycosaminoglycans
Funded at Wayne State University · NIH-10911784 · Data updated 2026-11-12
This study is exploring new ways to make important sugar molecules that could help improve treatments for diseases like cancer, making it easier for researchers to create these compounds that play a key role in our bodies.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Wayne State University NIH-funded |
| Lab location | 1 site (Detroit, United States) |
| Project start | September 1, 2023 |
| Project end | August 31, 2028 |
| Funding year | 2024 |
| Award (this year) | $524,144 |
| NIH project number | 5R35GM149213-02 |
| Project ID | NIH-10911784 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are patients with conditions that could be treated with therapies involving glycosaminoglycans or glycopeptides, particularly those related to cancer.
✕Less likely to help
Patients with conditions unrelated to glycosaminoglycans or glycopeptides may not benefit from this research.
What this research studies
This research focuses on developing innovative techniques to create glycosidic bonds, which are essential for forming complex sugar molecules known as glycosaminoglycans and glycopeptides. By using a special type of catalyst called phenanthrolines, the researchers aim to simplify the process of synthesizing these important biological compounds. This work could lead to better understanding and treatment options for various diseases, including cancer, by enhancing the production of biologically significant sugars. Patients may benefit from advancements in therapies that utilize these compounds.
Why it matters
Potential benefit: If successful, this research could lead to improved treatments for cancer and other diseases through the development of new therapeutic agents.
How similar studies have gone: Other research has shown promise in using similar catalytic approaches to synthesize complex sugars, indicating potential for success in this area.
Where this research is happening
-
Wayne State University
Detroit, United States Active
Researchers
- Principal investigator: Nguyen, Hien M — Wayne State University
- Study coordinator: Nguyen, Hien M
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.