NIH-funded research R01 grant

Creating new medicines from natural compounds

Official title: Synthesis of Biologically Active Terpenoids

Funded at Rice University · NIH-11010009 · Data updated 2026-11-12

This study is looking at how to create natural compounds called terpenoids that could help fight cancer and infections, with the hope of finding new treatment options for patients.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionRice University
NIH-funded
Lab location1 site (Houston, United States)
Project startFebruary 1, 2023
Project endJanuary 31, 2027
Funding year2025
Award (this year)$336,360
NIH project number5R01GM144489-04
Project IDNIH-11010009 on NIH RePORTER

Who could benefit from this research

Could help

Ideal candidates for this research are individuals with cancer or infections who may benefit from novel therapeutic agents.

Less likely to help

Patients who are not affected by cancer or infectious diseases may not receive direct benefits from this research.

What this research studies

This research focuses on synthesizing complex natural products, specifically terpenoids, which have shown potential as anti-cancer and anti-infective agents. By developing innovative synthetic methods, the researchers aim to overcome the challenges of limited availability and structural complexity of these compounds. Patients may benefit from new therapeutic options derived from these natural products, as the study explores their biological properties and potential applications in medicine.

Why it matters

Potential benefit: If successful, this research could lead to the development of new and effective treatments for cancer and infectious diseases.

How similar studies have gone: Previous research has successfully utilized natural products for drug development, indicating a promising potential for this approach.

Where this research is happening

  • Rice University
    Houston, United States
    Active

Researchers

  • Principal investigator: Sarlah, David — Rice University
  • Study coordinator: Sarlah, David

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
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Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.