Creating new medications to treat migraines effectively and safely

Developing multitarget enzyme inhibitors as safe and effective anti-migraine treatments

NIH-funded research California State University Hayward · NIH-10893039

This study is looking at new medications for migraine relief that work by targeting two key enzymes involved in pain and inflammation, aiming to offer a safer, non-opioid option for people who suffer from migraines.

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionCalifornia State University Hayward NIH-funded
Lab location1 site (Hayward, United States)
Project IDNIH-10893039 on NIH RePORTER

What this research studies

This research focuses on developing innovative medications for migraine treatment by creating dual inhibitors that target two specific enzymes involved in pain and inflammation. The approach aims to provide a non-opioid solution to migraine relief, addressing the limitations of current treatments that often lead to side effects or worsening headaches. By testing these new compounds in laboratory settings, the research seeks to identify effective alternatives that can improve the quality of life for migraine sufferers.

Who could benefit from this research

Good fit: Ideal candidates for this research are individuals who experience frequent migraines and have not found relief with existing treatments.

Not a fit: Patients who do not suffer from migraines or have other underlying conditions that complicate migraine treatment may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to safer and more effective migraine treatments that reduce pain without the risk of addiction or severe side effects.

How similar studies have performed: Previous research has shown promise in developing dual inhibitors for pain management, indicating potential success for this novel approach.

Where this research is happening

Hayward, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.