Creating new medications to treat migraines effectively and safely
Official title: Developing multitarget enzyme inhibitors as safe and effective anti-migraine treatments
Funded at California State University Hayward · NIH-10893039 · Data updated 2026-11-12
This study is looking at new medications for migraine relief that work by targeting two key enzymes involved in pain and inflammation, aiming to offer a safer, non-opioid option for people who suffer from migraines.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | California State University Hayward NIH-funded |
| Lab location | 1 site (Hayward, United States) |
| Project start | August 1, 2023 |
| Project end | June 30, 2027 |
| Funding year | 2024 |
| Award (this year) | $119,031 |
| NIH project number | 5R16GM150781-02 |
| Project ID | NIH-10893039 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are individuals who experience frequent migraines and have not found relief with existing treatments.
✕Less likely to help
Patients who do not suffer from migraines or have other underlying conditions that complicate migraine treatment may not benefit from this research.
What this research studies
This research focuses on developing innovative medications for migraine treatment by creating dual inhibitors that target two specific enzymes involved in pain and inflammation. The approach aims to provide a non-opioid solution to migraine relief, addressing the limitations of current treatments that often lead to side effects or worsening headaches. By testing these new compounds in laboratory settings, the research seeks to identify effective alternatives that can improve the quality of life for migraine sufferers.
Why it matters
Potential benefit: If successful, this research could lead to safer and more effective migraine treatments that reduce pain without the risk of addiction or severe side effects.
How similar studies have gone: Previous research has shown promise in developing dual inhibitors for pain management, indicating potential success for this novel approach.
Where this research is happening
-
California State University Hayward
Hayward, United States Active
Researchers
- Principal investigator: Kandasamy, Ram — California State University Hayward
- Study coordinator: Kandasamy, Ram
Related research
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.