Creating new materials for advanced cell imaging techniques
Official title: Development of polymer-based cell culture substrates for correlative light and electron microscopy (CLEM)
Funded at Wadsworth Center · NIH-10778718 · Data updated 2026-11-12
This study is working on creating special materials that help scientists better see and understand cells and tissues under a microscope, making it easier to track how they work and look in their natural state.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Wadsworth Center NIH-funded |
| Lab location | 1 site (Menands, United States) |
| Project start | September 30, 2024 |
| Project end | July 31, 2027 |
| Funding year | 2024 |
| Award (this year) | $303,582 |
| NIH project number | 1R01GM152716-01 |
| Project ID | NIH-10778718 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research would be individuals involved in biomedical research or those with conditions that require advanced cellular imaging techniques.
✕Less likely to help
Patients who are not engaged in scientific research or do not require detailed cellular analysis may not benefit from this research.
What this research studies
This research focuses on developing innovative polymer-based substrates that will enhance the process of correlative light and electron microscopy (CLEM). By creating a new type of porous substrate, the research aims to simplify the tracking and imaging of cells and tissues, allowing scientists to observe their structures and functions more effectively. The approach involves microfabrication techniques to design substrates that can maintain the cells' natural state while being compatible with advanced imaging methods. This could lead to significant improvements in how biological specimens are studied at the cellular level.
Why it matters
Potential benefit: If successful, this research could provide a powerful new tool for scientists to better understand cellular structures and functions, potentially leading to advancements in biomedical research and therapies.
How similar studies have gone: While the approach of using polymer-based substrates for imaging is innovative, similar methodologies in enhancing imaging techniques have shown promise in other studies.
Where this research is happening
-
Wadsworth Center
Menands, United States Active
Researchers
- Principal investigator: Sui, Haixin — Wadsworth Center
- Study coordinator: Sui, Haixin
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.