Creating new imaging tools for Alzheimer's disease detection
Development of class-IIa HDAC targeting PET probes for molecular imaging of disorders of the CNS
This study is testing a new imaging tool that helps doctors see how Alzheimer's disease is progressing in people, with the hope of improving early detection and finding better treatments for patients.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | State University New York Stony Brook NIH-funded |
| Lab location | 1 site (Stony Brook, United States) |
| Project ID | NIH-11178817 on NIH RePORTER |
What this research studies
This research focuses on developing a novel PET imaging probe that targets class-IIa histone deacetylases, which are believed to play a role in Alzheimer's disease. The goal is to validate this imaging tool for use in humans, allowing for real-time, non-invasive monitoring of Alzheimer's progression. By optimizing the production of this probe and conducting imaging studies, researchers aim to improve early detection and understanding of Alzheimer's disease. If successful, this approach could lead to better diagnostic methods and potential new treatments for patients.
Who could benefit from this research
Good fit: Ideal candidates for this research include individuals at risk for Alzheimer's disease or those showing early symptoms of cognitive decline.
Not a fit: Patients with advanced Alzheimer's disease or those not exhibiting any cognitive symptoms may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to earlier and more accurate detection of Alzheimer's disease, improving patient outcomes.
How similar studies have performed: Previous research has shown promise in using imaging probes for Alzheimer's detection, but this specific approach targeting class-IIa HDACs is novel.
Where this research is happening
Stony Brook, United States
- State University New York Stony Brook — Stony Brook, United States (Active)
Researchers
- Principal investigator: Turkman, Nashaat — State University New York Stony Brook
- Study coordinator: Turkman, Nashaat
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.