NIH-funded research R01 grant

Creating new imaging agents to improve surgery for pancreatic cancer

Official title: Development of contrast agents to facilitate image-guided surgery

Funded at University of Oklahoma Hlth Sciences Ctr · NIH-10931584 · Data updated 2026-11-12

This study is working on new tools to help surgeons see pancreatic tumors more clearly during surgery, making it easier to remove them completely and improve outcomes for patients with pancreatic cancer.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionUniversity of Oklahoma Hlth Sciences Ctr
NIH-funded
Lab location1 site (Oklahoma City, United States)
Project startSeptember 19, 2023
Project endAugust 31, 2028
Funding year2024
Award (this year)$563,640
NIH project number5R01CA281098-02
Project IDNIH-10931584 on NIH RePORTER

Who could benefit from this research

Could help

Ideal candidates for this research are patients diagnosed with pancreatic adenocarcinoma who are undergoing surgical resection.

Less likely to help

Patients with non-cancerous conditions or those who are not candidates for surgery may not benefit from this research.

What this research studies

This research focuses on developing advanced contrast agents that can help surgeons better identify pancreatic tumors during surgery. By using innovative imaging techniques, the study aims to enhance the visibility of tumors, particularly in challenging cases where traditional methods may fail. The approach involves investigating the use of specific biomarkers and imaging technologies to improve surgical outcomes for patients with pancreatic adenocarcinoma. The goal is to achieve more accurate tumor resections, minimizing the chances of leaving cancerous tissue behind.

Why it matters

Potential benefit: If successful, this research could lead to improved surgical outcomes and higher cure rates for patients with pancreatic cancer.

How similar studies have gone: Previous studies using fluorescent-guided surgery have shown promise, indicating that this approach could lead to significant advancements in surgical techniques for pancreatic cancer.

Where this research is happening

  • University of Oklahoma Hlth Sciences Ctr
    Oklahoma City, United States
    Active

Researchers

  • Principal investigator: Mcnally, Lacey R — University of Oklahoma Hlth Sciences Ctr
  • Study coordinator: Mcnally, Lacey R

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.