Creating new contrast agents for cellular imaging
Clonable Nanoparticles
['FUNDING_R01'] · COLORADO STATE UNIVERSITY · NIH-11050893
This study is working on special tiny particles made from proteins that can help scientists see details inside cells more clearly using electron microscopes, which could make it easier to understand how cells work.
Quick facts
| Phase | ['FUNDING_R01'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | COLORADO STATE UNIVERSITY (nih funded) |
| Locations | 1 site (FORT COLLINS, UNITED STATES) |
| Trial ID | NIH-11050893 on ClinicalTrials.gov |
What this research studies
This research focuses on developing cloneable nanoparticles that can enhance contrast in cellular electron microscopy. By using proteins to create these nanoparticles, the researchers aim to improve the identification of proteins within cells when viewed under an electron microscope. The approach involves encoding the properties of these nanoparticles in DNA, allowing for modifications that can tailor their characteristics. This could lead to better imaging techniques that help visualize cellular structures and functions more clearly.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals with conditions that require detailed cellular imaging for diagnosis or treatment monitoring.
Not a fit: Patients who do not require cellular imaging or have conditions that do not involve cellular abnormalities may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could significantly improve the ability to visualize cellular components, aiding in the diagnosis and understanding of various diseases.
How similar studies have performed: Other research has shown promise in using fluorescent proteins for imaging, but the development of cloneable contrast agents for electron microscopy is a novel approach.
Where this research is happening
FORT COLLINS, UNITED STATES
- COLORADO STATE UNIVERSITY — FORT COLLINS, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: ACKERSON, CHRISTOPHER JEFFRIES — COLORADO STATE UNIVERSITY
- Study coordinator: ACKERSON, CHRISTOPHER JEFFRIES
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.