Creating new compounds to improve cancer treatment
Official title: Synthesis of Carbohydrate-Phthalocyanine Conjugates for Biomedical Applications
Funded at Davidson College · NIH-10579707 · Data updated 2026-11-12
This study is looking at new ways to use special compounds to help treat liver cancer more effectively while causing less harm to healthy cells, so patients can have better treatment options with fewer side effects.
Quick facts
| Grant type | R15 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Davidson College NIH-funded |
| Lab location | 1 site (Davidson, United States) |
| Project start | September 15, 2022 |
| Project end | August 31, 2025 |
| Funding year | 2022 |
| Award (this year) | $402,695 |
| NIH project number | 1R15GM148916-01 |
| Project ID | NIH-10579707 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are individuals diagnosed with hepatocellular carcinoma or other forms of liver cancer.
✕Less likely to help
Patients with non-cancerous liver conditions or those not diagnosed with liver cancer may not benefit from this research.
What this research studies
This research focuses on developing carbohydrate-phthalocyanine conjugates that can be used as effective photosensitizers for treating liver cancer. By enhancing the solubility and selectivity of phthalocyanines, the research aims to improve their ability to target cancer cells while minimizing damage to healthy tissues. The approach involves a modular synthesis technique that allows for the creation of various compounds to evaluate their effectiveness in biological systems. Patients may benefit from improved treatment options that are more effective and have fewer side effects.
Why it matters
Potential benefit: If successful, this research could lead to more effective and targeted therapies for liver cancer patients.
How similar studies have gone: While there have been advancements in the use of phthalocyanines in cancer treatment, this specific approach of carbohydrate conjugation is relatively novel and has not been extensively tested.
Where this research is happening
-
Davidson College
Davidson, United States Active
Researchers
- Principal investigator: Snyder-Lee, Nicole Leigh — Davidson College
- Study coordinator: Snyder-Lee, Nicole Leigh
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.