Creating new compounds for potential Alzheimer's treatments
Official title: Development of Efficient Carbon Carbon Bond Formations for Novel Se-, S-, and O-Heterocycle Synthesis
Funded at Winston-Salem State University · NIH-10884345 · Data updated 2026-11-12
This study is looking for better ways to make new chemical compounds that could help treat Alzheimer's disease, using special reactions to create complex molecules that might be more effective for patients.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Winston-Salem State University NIH-funded |
| Lab location | 1 site (Winston-Salem, United States) |
| Project start | August 15, 2022 |
| Project end | July 31, 2026 |
| Funding year | 2024 |
| Award (this year) | $133,864 |
| NIH project number | 5R16GM145541-03 |
| Project ID | NIH-10884345 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are individuals with Alzheimer's disease or those at risk of developing it.
✕Less likely to help
Patients with conditions unrelated to Alzheimer's disease or those who do not respond to heterocyclic compounds may not benefit from this research.
What this research studies
This research focuses on developing efficient methods to create novel heterocyclic compounds, which are crucial for pharmaceutical applications, including potential treatments for Alzheimer's disease. The approach involves using metal-catalyzed reactions to form carbon-carbon bonds, enabling the synthesis of complex molecules that may have significant biological activity. By improving the efficiency and selectivity of these chemical processes, the research aims to generate new compounds that could lead to better therapeutic options for patients. The project also explores innovative multi-component reactions to streamline the synthesis of these important compounds.
Why it matters
Potential benefit: If successful, this research could lead to the development of new medications that improve treatment options for Alzheimer's disease.
How similar studies have gone: Other research has shown promise in developing heterocyclic compounds for therapeutic use, indicating a potential for success in this area.
Where this research is happening
-
Winston-Salem State University
Winston-Salem, United States Active
Researchers
- Principal investigator: Guo, Fenghai — Winston-Salem State University
- Study coordinator: Guo, Fenghai
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.