Creating new antiviral treatments for monkeypox virus
Official title: Development of novel antivirals against mpox (monkeypox) virus
Funded at University of Minnesota · NIH-11115784 · Data updated 2026-11-12
This study is working on creating new medicines to fight the monkeypox virus, aiming to find better treatments for people who might be affected by outbreaks.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Minnesota NIH-funded |
| Lab location | 1 site (Minneapolis, United States) |
| Project start | June 14, 2024 |
| Project end | April 30, 2029 |
| Funding year | 2025 |
| Award (this year) | $767,359 |
| NIH project number | 5R01AI183580-02 |
| Project ID | NIH-11115784 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research include individuals at risk of monkeypox infection or those who have been diagnosed with the virus.
✕Less likely to help
Patients who are not at risk for monkeypox or those with other unrelated viral infections may not benefit from this research.
What this research studies
This research focuses on developing novel antiviral medications specifically targeting the monkeypox virus, which has shown potential for outbreaks worldwide. The team will utilize a combination of medicinal chemistry and virology to enhance the effectiveness of existing antiviral compounds. By employing advanced assays, they aim to identify and refine promising antiviral candidates that can be tested for safety and efficacy. This work is crucial as current treatments for monkeypox are limited and often ineffective.
Why it matters
Potential benefit: If successful, this research could lead to effective antiviral treatments for monkeypox, reducing morbidity and mortality associated with the virus.
How similar studies have gone: Previous research has shown promise in developing antiviral treatments for related viruses, indicating potential for success in this novel approach.
Where this research is happening
-
University of Minnesota
Minneapolis, United States Active
Researchers
- Principal investigator: Wang, Zhengqiang — University of Minnesota
- Study coordinator: Wang, Zhengqiang
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.