Creating new antiviral treatments for monkeypox virus

Development of novel antivirals against mpox (monkeypox) virus

NIH-funded research University of Minnesota · NIH-11115784

This study is working on creating new medicines to fight the monkeypox virus, aiming to find better treatments for people who might be affected by outbreaks.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionUniversity of Minnesota NIH-funded
Lab location1 site (Minneapolis, United States)
Project IDNIH-11115784 on NIH RePORTER

What this research studies

This research focuses on developing novel antiviral medications specifically targeting the monkeypox virus, which has shown potential for outbreaks worldwide. The team will utilize a combination of medicinal chemistry and virology to enhance the effectiveness of existing antiviral compounds. By employing advanced assays, they aim to identify and refine promising antiviral candidates that can be tested for safety and efficacy. This work is crucial as current treatments for monkeypox are limited and often ineffective.

Who could benefit from this research

Good fit: Ideal candidates for this research include individuals at risk of monkeypox infection or those who have been diagnosed with the virus.

Not a fit: Patients who are not at risk for monkeypox or those with other unrelated viral infections may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to effective antiviral treatments for monkeypox, reducing morbidity and mortality associated with the virus.

How similar studies have performed: Previous research has shown promise in developing antiviral treatments for related viruses, indicating potential for success in this novel approach.

Where this research is happening

Minneapolis, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.