Creating new antioxidant compounds to reduce chronic inflammation
Official title: Engineering hydrophilic/amphiphilic Vitamin B6-based super antioxidant dendrimers for controlling chronic inflammation
Funded at Central Michigan University · NIH-11037056 · Data updated 2026-11-12
This study is exploring new antioxidant compounds called dendrimers that could help reduce chronic inflammation, and it's designed for people dealing with inflammatory conditions.
Quick facts
| Grant type | R15 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Central Michigan University NIH-funded |
| Lab location | 1 site (Mount Pleasant, United States) |
| Project start | September 1, 2022 |
| Project end | August 31, 2025 |
| Funding year | 2024 |
| Award (this year) | $24,064 |
| NIH project number | 3R15GM147862-01S2 |
| Project ID | NIH-11037056 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research include individuals suffering from chronic inflammatory conditions such as arthritis, asthma, or cardiovascular diseases.
✕Less likely to help
Patients with acute inflammatory conditions or those not affected by chronic inflammation may not benefit from this research.
What this research studies
This research focuses on developing innovative antioxidant compounds known as dendrimers, which are designed to combat chronic inflammation. By utilizing advanced microwave synthesis techniques, the researchers aim to create these compounds quickly and efficiently while ensuring they are safe for biological use. The dendrimers are engineered to trap harmful metal ions, enhancing their antioxidant properties without introducing contaminants. This approach could lead to new treatments for various inflammatory conditions affecting patients.
Why it matters
Potential benefit: If successful, this research could provide patients with new therapeutic options to manage chronic inflammation and related diseases.
How similar studies have gone: While the use of dendrimers in medical applications is a growing field, this specific approach utilizing microwave synthesis and copper-free methods is relatively novel.
Where this research is happening
-
Central Michigan University
Mount Pleasant, United States Active
Researchers
- Principal investigator: Lee, Choon Young — Central Michigan University
- Study coordinator: Lee, Choon Young
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.